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Sale!

Percocet

$459.00$899.00

The drug therapy have the potential to reduce the respiratory drive of the
patient and can cause resultant retention of CO2, this further might lead to
increase in intracranial pressure and in those cases monitoring the patients for
signs and symptoms of sedations and respiratory depression is important. It is
also not advised to use this drug therapy in patients with impaired
consciousness or coma.

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PERCOCET: DRUG COMBINATION, MEDICAL USES, ADVERSE EFFECTS AND SIDE EFFECTS.

INTRODUCTION

Percocet is the brand name for the drug oxycodone/paracetamol, it is a fixed combination of drug opioid analgesic oxycodone and paracetamol (acetaminophen). Mainly used in treatment of moderate to severe type of pain, it also has many other therapeutic effects. In this article we will look at Percocet, it’s clinical relevancy, therapeutic effects and adverse reactions.

CLINICAL DATA REGARDING THE DRUG COMBINATION PERCOCET

Combination drug: oxycodone(opioid analgesic) and paracetamol (aniline analgesic)
Trade name: Percocet and others.
Route of drug administration: mostly commonly used oral route.
Medicinal and therapeutic uses:
Percocet combination is used for management of acute pain, which is severe enough in intensity to require the intake of drugs like opioid analgesic, the total permitted doses should not exceed 4g/day. It is also given to patients who are suffering from chronic pain whose administration schedule is dosing around the clock, this combination drug therapy is also given to patients who suffer from intermittent or breakthrough type of pain.

PERCOCET COMBINATION: SIDE EFFECTS AND ADVERSE REACTIONS.

Percocet is highly contraindicated in patients with hypersensitivity, paralytic ileus, gastrointestinal obstruction (suspected or known case) , acute to severe
type of bronchial asthma or hypercarbia , Chronic obstructive pulmonary disorders (COPD) and / or significant respiratory depression and disorders The most common side effects and adverse reactions surrounding the use of drug combination includes lightheadedness, Dizziness, drowsiness or sedation, vomiting, feeling of nausea, euphoria and dysphoria, severe to moderate constipation, pruritus, eruptions of skin and urticarial, necrosis of feral hepatic type and renal tubular necrosis ( though the cases of necrosis are very rarely occurring, ad this can be associated with higher and chronic use of the drug acetaminophen.

WARNINGS REGARDING THE USE OF THE DRUG OXYCODONE

There is an increase threat and risk of addiction, abuse and misuse of the drug oxycodone due to which there can be overdose and it can be life threatening,
therefore assessing the patient for risk before prescribing the drug is important and monitoring the drug regularly to check for development of symptoms of
abuse is necessary. There are chances of development of serious, life threatening and fatal respiratory distress, if the drug is accidentally consumed by children, it can lead to fatal overdose syndrome.prolonged usage during pregnancy can be life threatening as it may cause “neonatal opioid withdrawal syndrome”

WARNINGS REGARDING THE USE OF ACETAMINOPHEN

There are high chances of development of hepatotoxicity if the dosage per day exceeds 4g/day. Acetaminophen is often also in cases of acute liver failure ,
which might lead to transplantation of liver in some cases.

CAUTION AND WARNING

Caution should be maintained while giving the drug combination of oxycodone and paracetamol that is the drug Percocet as it may develop severe hypotension which includes orthostatic hypotension and syncope in ambulatory patients, in patients who are suffering from circulatory shock, drug therapy may cause vasodilation, which can even further reduce the cardiac output and blood pressure of the patient. The drug therapy have the potential to reduce the respiratory drive of the patient and can cause resultant retention of CO2, this further might lead to increase in intracranial pressure and in those cases monitoring the patients for signs and symptoms of sedations and respiratory depression is important. It is also not advised to use this drug therapy in patients with impaired
consciousness or coma. This combination drug is contraindicated in gastrointestinal obstructive patients as it causes severe spasm in the sphincter of oddi, this opioids may also increase the levels of serum Amylase. Hence, monitoring the patients with disease of biliary tract, including acute pancreatitis and worsening symptoms. Though the risk of life threatening or fatal distress in respiration can occur throughout the course of the intake of the drug, the risk is greatest during the initiation of the therapy and monitoring the patients closely during this phase is important especially within the first 24 to 72 hour of initiation.

Percocet combination is available in form of tablets or capsules, for oral route of administration, and dosage of Percocet should highly be prescribed
according to individuals need , conditions, age and response to the treatment being provided. In patients with liver and kidney disease and elderly and
geriatric population, dosage adjustment is a crucial factor. It is of utmost importance to follow the required amount of dose and not exceed it. The administered dose should always be checked for side effects and reactions if the body is producing. And the healthcare professional create an awareness for the patients to let them know the potential side effects and harms the drug can cause. The potential to develop the physical dependency during pregnancy and after pregnancy is higher than usual and utmost care should be taken during times like this.

CONCLUSION:

The drug therapy for the combination of paracetamol and oxycodone which is traded by the name Percocet has therapeutic uses in treatment and management of pain ranging from mild, acute to moderate and severe, this can also be used in treating intermittent and breakthrough type of pain, Percocet though works efficiently on the pain of a patient, it also produces various side effects and adverse reactions on the body of a patient especially if he/ she already suffers from a co morbid condition like retention of CO2, hepatotoxicity, brain tumours, gastrointestinal disorders and etc. care is important immediately after administering the dose of Percocet, since, most of the side effects and symptoms of unsustainable risks are shown immediately or within 24 to 72 hours of administration of the drug. Seeking of professional help is important when starting the doses of Percocet and assessment and evaluation of all the risk factors. Patient should be well aware about all the potential risks and damages the drug could produce.

Quantity

90 Pills, 180 Pills

Delivery Time

3 to 5 Days, 8 to 10 Days

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